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MEDIA - CLARITY Compatible Computer Devices



Device types / MEDIA / CLARITY




Description extracted from Wikipedia:

CLARITY is a method of making brain tissue transparent using acrylamide-based hydrogels built from within, and linked to, the tissue, and as defined in the initial paper, represents "transformation of intact biological tissue into a hybrid form in which specific components are replaced with exogenous elements that provide new accessibility or functionality". When accompanied with antibody or gene-based labeling, CLARITY enables highly detailed pictures of the protein and nucleic acid structure of organs, especially the brain. It was developed by Kwanghun Chung and Karl Deisseroth at the Stanford University School of Medicine. Subsequent published papers have applied the CLARITY method of building acrylamide-based tissue-gel hybrids within tissue for improved optical and molecular access to Alzheimer's disease human brains, mouse spinal cords, multiple sclerosis animal models, and plants. CLARITY has also been combined with other technologies to develop new microscopy methods including confocal expansion microscopy and CLARITY-optimized light sheet microscopy (COLM).